925 Sterling Silver Mano de Fatima Necklace with Simulated Diamond Stones. The hamsa is a Middle Eastern symbol dating back to prehistoric times designed to give protection from the evil eye, bad luck that results from the attention or jealousy. An alternative Islamic name for this charm is the Hand of Fatima, in reference to Fatima Zahra, the daughter of Muhammed. An alternative Jewish name is the Hand of Miriam, in reference to Miriam, the sister of Moses and Aaron.